Breast Cancer Breakthroughs: SABCS 2025 Highlights

Experts in Dana-Farber’s Breast Oncology Center discuss highlights in breast cancer research innovation presented at SABCS 2025  in San Antonio, Texas providing state-of-the-art information on experimental biology, etiology, prevention, diagnosis, and therapy of breast cancer and premalignant breast disease.  


Paolo Tarantino, MD discusses the DATO - Base study

Paolo Tarantino, MD, of Dana-Farber Cancer Institute, presented new findings from the DATO-Base study examining treatment with the ADC Dato-DXd for women with leptomeningeal disease. Breast cancer is the most common cancer linked to this ...

Erica Mayer, MD discusses results from TBCRC 56 study

Erica Mayer, MD, of Dana-Farber Cancer Institute shared results from TBCRC 56, showing presurgical treatment with a PARP inhibitor + anti-PD1 combo in patients with gBRCAm early triple-negative breast cancer resulted in a pCR rate of 50%. ...
Erica Mayer, MD, MPH

Erica Mayer, MD, MPH

Medical Oncology

Ann Partridge, MD discusses YES study

Breast cancer survivors who used a novel mobile health intervention to self-manage post-treatment symptoms were able to improve their quality of life and reduce the burden of common symptoms, according to results of the YES study presented ...
Ann Partridge, MD

Ann Partridge, MD

Medical Oncology

Rachel Freedman, MD discusses phase 2 ATOP study

Dana-Farber Cancer Institute's Rachel Freedman, MD, presents results from the phase 2 ATOP study showing older patients with HER2+ breast cancer receiving adjuvant T-DM1 had a favorable 5-year survival with manageable toxicity. ATOP is ...
Rachel Freedman, MD

Rachel Freedman, MD

Medical Oncology

Stefania Morganti, MD discusses ctDNA study

Ultrasensitive detection of minimal residual disease using ctDNA can help predict the duration of response to HER2 targeted therapy in patients with metastatic breast cancer, according to a study presented by Stefani Morganti, MD, of Dana-Farber ...